An Update on the Management of Nosocomial Pneumonia

Author:

Gupta Rahul1,Wargo Kurt A.2

Affiliation:

1. Department of Medicine, Meharry Medical College, Nashville, Tennessee, Division of General Internal Medicine and Public Health, Vanderbilt University School of Medicine, Nashville, Tennessee,

2. Auburn University Harrison School of Pharmacy, Auburn, Alabama, Division of Internal Medicine, UAB School of Medicine- Huntsville Regional Medical Campus, Huntsville, Alabama

Abstract

Nosocomial pneumonia is the second most common hospital-acquired infection, after urinary tract infection; however, it carries with it a mortality rate estimated to be between 20% and 50%. Furthermore, patients with nosocomial pneumonia are hospitalized for an additional 7 to 9 days with an attributable cost of $40 000 or more per patient compared to patients without nosocomial pneumonia. While treatment options vary, initial empiric treatment of nosocomial pneumonia should include antimicrobials that will have activity against the organisms that will likely be encountered, including, but not limited to, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter species, Klebsiella pneumoniae, Enterobacter subspecies, Serratia marcescens, and Stenotrophomonas maltophilia. During a time of increasing resistance, it is crucial that early recognition along with appropriate treatment and dosing strategies are employed to achieve successful outcomes. The goal of this article is to update clinicians about nosocomial pneumonia and provide information regarding caveats to selecting and dosing antimicrobials, so informed decisions can be made when treating this serious condition.

Publisher

SAGE Publications

Subject

Pharmacology (medical)

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Postoperative Pneumonia-Prevention Program for the Inpatient Surgical Ward;Journal of the American College of Surgeons;2010-04

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