High-Technology Home Pharmacotherapy, I: An Overview of Antiinfective and Antineoplastic Therapies

Abstract

Home care has evolved into a highly technical support system caring for the more acutely ill patient who requires specialized medical attention. Almost every drug is a candidate for home-care administration if adequate patient selection and monitoring criteria are met. Home parenteral antimicrobial therapy has progressed beyond simple intravenous (IV) drip administration. New routes and techniques, and unusual doses and intervals are commonly encountered. Newer infusion devices have enabled antibiotic and other therapies to be accomplished more easily. Parenteral chemotherapy at home has been given by some unusual routes and administered continuously. Management of the potentially severe side effects of antineoplastic therapy has also been successfully accomplished in the home. This article addresses the considerations for initiating home parenteral therapy and provides an overview of the management of antimicrobial and antineoplastic therapies at home.