Severe polymorphic erythema due to interferon α-2b during treatment of hairy cell leukemia-Reference-Cited by-同舟云学术

Severe polymorphic erythema due to interferon α-2b during treatment of hairy cell leukemia

Published:2019-06-27 Issue:7 Volume:47 Page:3453-3457
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Li Chen¹^ORCID,Geng Hui²,Ji Linhua²,Jiang Yan²,Ma Xiaojing²,Yin Qichao²,Xiong Hua²

Affiliation:

1. Qinghai University Graduate School, Xining, China

2. Department of Haematology, the Affiliated Hospital of Qinghai University, Xining, Qinghai, China

Abstract

A 54-year-old woman with hairy cell leukemia developed severe polymorphic erythema and blisters on the trunk and limbs after injection of interferon (IFN) α-2b. Skin biopsy revealed lymphocytic exocytosis and perivascular lymphocytic infiltrate in the dermis, and the lesions improved after methylprednisolone pulse therapy. Although injection-site reactions have been observed after injection of IFNα-2b, this is the first report of a widespread cutaneous reaction to IFNα-2b.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0300060519856158

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1. Skin changes in hairy cell leukemia;Annals of Hematology;2020-11-20

2. Interferon-alpha-2b;Reactions Weekly;2019-09