Patient Preference for a Combined Diuretic/Potassium Regimen: Burinex K

Author:

Murphy J E1,Maneksha S2,Brodie N H3

Affiliation:

1. General Practitioner, Northampton, England

2. General Practitioner, Hornsey, London, England

3. General Practitioner, Brighton, England

Abstract

A cross-over investigation was performed to compare patient preference of potassium supplement tablets. Seventy-seven patients requiring diuretics for the long-term management of congestive heart failure were randomly allotted to two therapeutically equivalent regimens; either Burinex K tablets + a placebo Burinex tablet or Slow K tablets + an active Burinex tablet. Forty-two patients found Burinex K easier to swallow, 9 found Slow K easier to swallow, and 26 patients expressed no preference. There was an appreciably higher incidence of gastro-intestinal upset when patients were taking Slow K. These results indicate that when long-term diuretic/potassium supplement therapy is required, Burinex K is a more acceptable regimen to the patient than one in which diuretic + Slow K are given separately.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

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