Changes in Oxidative Metabolism of Guinea Pig Brain Cortex Slices in the Presence of Meso-Inositol Hexanicotinate and Nicotinic Acid-Reference-Cited by-同舟云学术

Changes in Oxidative Metabolism of Guinea Pig Brain Cortex Slices in the Presence of Meso-Inositol Hexanicotinate and Nicotinic Acid

Published:1973-03 Issue:3 Volume:1 Page:192-193
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Joanny P¹,Balansard P¹,Legros J²

Affiliation:

1. Laboratoire de Physiologie, Faculté de Médicine Nord, Bd Paul Dramard. 13 Marseille, France

2. Centre de Recherche Winthrop, B P 40, Zone Industrielle, 21600 Longvic, France

Abstract

Both nicotinic acid and meso-inositol hexanicotinate significantly decrease oxygen uptake of isolated guinea-pig cerebral cortex. This inhibition is tentatively correlated to the already described protective effect against hypoxia produced by these compounds in vivo.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030006057300100310

Reference6 articles.

1. A simple scintillation counting technique for assaying C14O2 in a Warburg flask

2. Arteriosclerosis and hypoxia

3. SUBSTRATES AND THE POTASSIUM AND SODIUM LEVELS OF GUINEA PIG:. EFFECTS OF APPLICATION OF ELECTRICAL PULSES, OF INHIBITORS AND OF ANOXIA

4. Meso-Inositol Hexanicotinate Induced Protection against Experimental Anoxia and Oedema

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1. Biologically active nonlipid derivatives ofMYO-inositol and prospects for their use in drug design (a review);Pharmaceutical Chemistry Journal;1996-03