Affiliation:
1. Royal Infirmary Edinburgh, Lauriston Place, Edinburgh, EH3 9YW, Scotland
Abstract
The effect of sublingual buprenorphine (0.4 mg) was compared with that of oral dihydrocodeine (60 mg) in patients experiencing post-operative pain following general surgery. Pain relief was significantly greater for buprenorphine than for dihydrocodeine, based on both peak effect and total effect. Both treatments were effective from 30 minutes. There was evidence that buprenorphine had a slightly slower onset of action, but a distinctly longer duration of action, than dihydrocodeine. Unwanted effects were similar for both treatments.
Subject
Biochemistry (medical),Cell Biology,Biochemistry,General Medicine
Reference7 articles.
1. Analgesic effects of sublingual buprenorphine
2. Relief of pain after surgery.
3. Houde R W (1979) In: Advances in Pain Research and Therapy Vol 2. Ed Bonica J J, Ventafridda V. Raven Press, New York. p 266.
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