Treatment and nursing care of a patient diagnosed with malignant hyperthermia after general anesthesia: a case report

Author:

Tian Li1,Li Hanfei1ORCID,Zhang Xiufen1,Liao Linzi1,Wu Juan1,Pei Xiang1

Affiliation:

1. State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, and Postanesthesia Care Unit; West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China

Abstract

Malignant hyperthermia (MH), characterized by severe myoclonus, pyrexia, tachycardia, hypertension, elevated muscle enzymes, and hypercapnia, often occurs in patients with congenital deformities or genetic disorders. Although the reported incidence rate is as low as 1:5000 to 1:100,000, patients with MH exhibit rapid aggravation and an elevated mortality rate. Thus, MH is associated with substantial perioperative risk. Successful treatment of patients with MH largely depends on early diagnosis and timely effective treatment. This clinical report provides a detailed description of a patient with newly diagnosed MH who developed a rapid rise in body temperature, end-tidal carbon dioxide, and heart rate during maxillary osteotomy. After successful rescue, the patient recovered smoothly during the postoperative period, indicating the importance of intraoperative monitoring, early diagnosis, effective treatment, and postoperative monitoring. This case is expected to serve as a reference for future interventions and healthcare practices in managing other patients with MH.

Funder

Sichuan Province Science and Technology Plan Projects

Publisher

SAGE Publications

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1. Sevoflurane;Reactions Weekly;2024-07-20

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