Affiliation:
1. Medizinischen Universitätsklinik und Poliklinik der Berufsgenossenschaftlichen Krankenanstalten ‘Bergmannsheil Bochum’, Germany
Abstract
Thirty patients with acute exacerbations of chronic obstructive bronchitis were treated sequentially with 10-day courses of BRL 25000 (750 mg t.i.d.) and doxycycline (200 mg on Day 1, then 100 mg daily) in alternating order. BRL 25000 is a formulation of amoxycillin 500 mg with clavulanic acid 250 mg, a β-lactamase inhibitor which protects amoxycillin from destruction by these enzymes. BRL 25000 gave clinical results which compared favourably with those of doxycycline and should prove a useful antibiotic for patients with chronic obstructive bronchitis, especially against infections due to problem organisms.
Subject
Biochemistry (medical),Cell Biology,Biochemistry,General Medicine
Cited by
11 articles.
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