Comparative Trial of Fucidin Ointment and Fucidin Cream in Skin Sepsis

Abstract

A study has been conducted on 101 patients with superficial skin sepsis comparing the effectiveness of topical treatment with 2% sodium fusidate ointment and a new preparation containing 2% fusidic acid in a cream base. The results showed that both topical preparations were equally effective in terms of the number of days for healing to take place and in the subjective assessment of the clinical response. Bacteriological investigation of the swabs from ninety-one patients showed Staphylococcus aureus to be the most frequently isolated pathogen. Both preparations were well tolerated and no adverse reactions were observed. It is suggested that the new 2% fusidic acid cream is particularly suitable for use on lesions requiring no dry dressing, whereas the 2% sodium fusidate ointment is preferred for those conditions where a dressing is applied.