Free flap transplantation combined with Ilizarov bone transport for the treatment of severe composite tibial and soft tissue defects

Author:

Li Runguang12345ORCID,Zeng Canjun1234,Yuan Song5,Chen Yirong67,Zhao Shanwen1234,Ren Gao-hong67

Affiliation:

1. Department of Foot and Ankle Surgery, Center for Orthopaedic Surgery, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China

2. Orthopaedic Hospital of Guangdong Province, Guangzhou, China

3. Academy of Orthopaedics, Guangdong Province, Guangzhou, China

4. Guangdong Provincial Key Laboratory of Bone and Joint Degenerative Diseases, Guangzhou, China

5. Department of Orthopedics, Linzhi People’s Hospital, Linzhi, China

6. Division of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China

7. Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Abstract

Objective To evaluate the clinical efficacy of free flap transplantation combined with Ilizarov bone transport in the treatment of severe composite tibial and soft tissue defects. Methods We retrospectively analyzed the clinical data of 40 patients with severe composite tibial and soft tissue defects who underwent free flap transplantation combined with Ilizarov bone transport. The clinical efficacy was evaluated according to the following criteria: success rate of wound repair by free flap transplantation, incidence or recurrence rate of deep infection, healing rate of bone defects and external fixation index, incidence of complications, and functional score of affected extremities. Results All infections were generally well controlled by radical debridement and negative-pressure therapy, and all 40 patients’ wounds healed after repair and reconstruction of the tibia and soft tissues. Postoperative complications were alleviated by active treatment. The mean external fixation time was 12.83 ± 2.85 months, and the external fixation index was 1.55 m/cm. According to the Association for the Study and Application of Methods of Ilizarov (ASAMI) score, an excellent or good functional outcome was attained in 85% of patients. Conclusion Free flap transplantation combined with Ilizarov bone transport is an effective treatment for severe composite tibial and soft tissue defects.

Funder

Natural Science Foundation of Guangdong Province

Shanghai Wang Zhengguo trauma medical development foundation

Clinical Research Projects of President Foundation of Nanfang Hospital, Southern Medical University

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

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