Rifaximin, a Rifamycin Derivative for Use in the Treatment of Intestinal Bacterial Infections in Seriously Disabled Patients

Abstract

This study reports the results of an evaluation of the effectiveness and tolerability of rifaximin, an intestinal topical antibiotic. It was administered using a nasogastric tube in patients with severe enterocolitis and bacterial superinfections causing intestinal inflammatory diseases and portosystemic encephalopathy. The drug proved highly effective clinically and produced neither local nor systemic side-effects. E’ stata valutata l'efficacia e la tollerabilita delia rifaximina, un antibiotico ad azione topica intestinale, somministrata tramite sondino nasogastrico in pazienti affetti da gravi enterocoliti, sovrainfezioni batteriche in corso di malattie infiammatorie intestinali ed encefalopatia porto-sistemica. Oltre all'ottima efficacia clinica si segnala l'assenza di effetti collaterali, locali e sistemici, di questo farmaco.