Translational value of partial resection of the pulmonary artery wall for congenital heart disease-induced bronchial compression

Author:

Wu Xiangyang1,Zhu Jie2,Liu Hao1,Chen Wensheng1,Wei Yalin1,Guan Xinqiang1,Zhang Yanchun1,Tao Pengxian1,Gao Bingren1ORCID

Affiliation:

1. Department of Cardiac Surgery, Second Hospital of Lanzhou University, Lanzhou, Gansu, China

2. Department of Pediatrics, Second Hospital of Lanzhou University, Lanzhou, Gansu, China

Abstract

Objective This study was performed to evaluate the clinical efficacy and safety of a novel surgical procedure in treating tracheal or bronchial compression related to severe congenital heart disease. Methods The clinical data of 28 patients with tracheal or bronchial compression related to severe congenital heart disease were retrospectively analyzed. In the control group, 12 patients underwent surgery for congenital cardiac malformations. In the treatment group, 16 patients underwent surgery for congenital cardiac malformations combined with partial resection of the pulmonary artery wall. The cardiothoracic ratio, pulmonary arterial pressure, left ventricular end-diastolic dimension, diameter of the pulmonary artery, and diameter of the trachea in the stenotic segment were quantitatively measured before and 9 days after the operation. Results The diameter of the pulmonary artery and diameter of the trachea in the stenotic segment were almost restored to the normal range in the treatment group. Patients in the treatment group recovered more rapidly and effectively than those in the control group. Conclusion Partial resection of the pulmonary artery wall is an efficacious and safe technique in the treatment of tracheal or bronchial compression related to severe congenital heart disease.

Funder

Gansu Provincial Health Department Research Plan

Longyuan Youth Innovative Talents Support Programs

National Nature Science Foundation of China

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

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