Serological analysis of autoantibody mimicking anti-Rh(e) specificity: a case report-Reference-Cited by-同舟云学术

Serological analysis of autoantibody mimicking anti-Rh(e) specificity: a case report

Published:2024-06 Issue:6 Volume:52 Page:
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Dong Kedi¹^ORCID,Huang Xinyu²,Ying Qiming¹,Lv Dingfeng¹

Affiliation:

1. Department of Blood Transfusion, The First Affiliated Hospital of Ningbo University, No. 59, Liuting Street, Ningbo, Zhejiang, P. R. China

2. Transfusion Medicine Research Institute, Blood Center of Zhejiang Province, No. 789, Jianye Road, Hangzhou, Zhejiang, P. R. China

Abstract

Mimicking antibodies are described as autoantibodies with the “wrong” specificity, possessing both specificity and panreactivity. We report the case of a female patient with suspected hemolytic anemia in whom an autoantibody mimicking anti-Rh(e) specificity was found in both plasma and red blood cell samples. Mimicking antibodies are not usually identified in the clinic; however, it is still necessary to determine the specificity of mimicking antibodies to avoid antigen-positive blood transfusions and achieve maximum transfusion compatibility.

Funder

Natural Science Foundation of Ningbo Municipality

Medical and Health Research Project of Zhejiang Province

Publisher

SAGE Publications

Link

https://journals.sagepub.com/doi/pdf/10.1177/03000605241258881

Reference9 articles.

1. A red blood cell autoantibody with mimicking anti-E specificity

2. Warm autoimmune hemolytic anemia with mimicking anti-c and -E specificities

3. Warm autoimmune hemolytic anemia with mimicking anti-e specificity causing intravascular hemolysis in a chronic ITP patient

4. Red cell autoantibody mimicking anti-C specificity: a rare manifestation

5. Studies of antibodies in the sera of patients who have made red cell autoantibodies