Treatment of Essential Hypertension with a Combination of Propranolol and Bendrofluazide-Reference-Cited by-同舟云学术

Treatment of Essential Hypertension with a Combination of Propranolol and Bendrofluazide

Published:1980-01 Issue:1 Volume:8 Page:34-37
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Solomon L R¹,Dawes P M²

Affiliation:

1. Tutor in Medicine, Manchester Royal Infirmary, Manchester, England

2. Medical Department, ICI Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire, England

Abstract

The effect of conventional propranolol and bendrofluazide tablets given twice daily has been compared with an equivalent dosage combined in a single capsule given twice daily in fourteen patients with essential hypertension. Good blood pressure control was achieved on both regimes in the majority of patients and there was no significant difference in treatment response between the two regimes. Use of the combined capsule is convenient and may improve patient compliance.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030006058000800106

Reference8 articles.

1. Beta-adrenoceptor blocking drugs and diuretics in hypertension.

2. Antihypertensive Effect and Side-effects of Bendroflumethiazide and Propranolol

3. Pharmacological Basis for Combination Therapy of Hypertension

4. Propranolol in hypertension: a dose-response study.

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1. Effectiveness of fixed-dose combination therapy in hypertension: systematic review and meta-analysis;Archives of Medical Science;2018

2. Free versus Fixed Combination Antihypertensive Therapy for Essential Arterial Hypertension: A Systematic Review and Meta-Analysis;PLOS ONE;2016-08-22

3. Bidirectional Adherence Changes and Associated Factors in Patients Switched From Free Combinations to Equivalent Single-Pill Combinations of Antihypertensive Drugs;Hypertension;2014-05

4. Compliance, Safety, and Effectiveness of Fixed-Dose Combinations of Antihypertensive Agents;Hypertension;2010-02

5. Pharmacokinetics of bendroflumethiazide alone and in combination with propranolol and hydralazine;European Journal of Clinical Pharmacology;1982