Impact of worst pattern of invasion on prognosis of oral squamous cell carcinoma: a systematic review and meta-analysis-Reference-Cited by-同舟云学术

Impact of worst pattern of invasion on prognosis of oral squamous cell carcinoma: a systematic review and meta-analysis

Published:2023-10 Issue:10 Volume:51 Page:
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Binmadi Nada O.¹^ORCID,Mohamed Yassmin A.²

Affiliation:

1. Department of Oral Diagnostic Sciences, King Abdulaziz University Faculty of Dentistry, Jeddah, Saudi Arabia

2. Oral Maxillofacial Surgery and Oral Pathology Department, Faculty of Dentistry, University of Khartoum

Abstract

Objective The relationship between the worst pattern of invasion (WPOI) and the prognosis of oral squamous cell carcinoma (OSCC) remains controversial. This systematic review and meta-analysis was performed to determine the impact of the WPOI on the prognosis of OSCC. Methods Studies from six databases were assessed for quality using the Newcastle–Ottawa Scale, and data were analyzed using Stata software. Results Eighteen studies involving 3954 patients showed that patients with a WPOI of 4 to 5 had significantly worse overall survival, disease-specific survival, and disease-free survival than patients with a WPOI of 1 to 3. Significant associations of the WPOI with locoregional recurrence and mortality were found. Conclusion A higher WPOI was significantly associated with a worse prognosis of OSCC across various outcomes. Incorporating the WPOI into standard histopathological assessments may guide personalized treatments and improve outcomes.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/03000605231206260

Reference31 articles.

1. Tumor Budding and Worse Pattern of Invasion Can Predict Nodal Metastasis in Oral Cancers and Associated With Poor Survival in Early-Stage Tumors

2. For early-stage oral tongue cancer, depth of invasion and worst pattern of invasion are the strongest pathological predictors for locoregional recurrence and mortality

3. Depth of invasion, tumor budding, and worst pattern of invasion: Prognostic indicators in early‐stage oral tongue cancer

4. The prognostic role of histologic grade, worst pattern of invasion, and tumor budding in early oral tongue squamous cell carcinoma: a comparative study

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1. The impact of tumor budding and single-cell invasion on survival in patients with stage III/IV locally advanced oral squamous cell carcinoma- results from a prospective cohort study;Frontiers in Oncology;2024-04-29

2. Association of worst pattern of invasion in oral squamous cell carcinoma with clinicopathological parameters;Journal of Medicine, Surgery, and Public Health;2023