Pulmonary blastoma with a good prognosis: a case report and review of the literature

Author:

Liu Qingru1ORCID,Li Fengchao1,Wang Lulu1,Lv Feng1,Yin Qianqian1,Liu Guangzhen1,Chen Wen2

Affiliation:

1. Department of Pathology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China

2. Department of Pathology, The 8th Medical Center, Chinese PLA General Hospital, Beijing, China

Abstract

Pulmonary blastoma (PB) is a rare, highly malignant tumor prone to distant metastasis and recurrence, and the prognosis of these patients is often poor. We report a case of metastatic PB with a good prognosis with the aim of providing data to support a clinical diagnosis and treatment. In December 2015, a 43-year-old male patient was admitted to our hospital because of a cough and blood-stained sputum. Positron emission-computed tomography showed massive high-density imaging in the lower lobe of the right lung, with a maximum cross-section of 76 × 58 mm. Thoracoscopic-assisted right lower lobectomy with lymph node dissection was performed. After 1 month, computed tomography showed a high possibility of metastasis. The patient then received docetaxel and cisplatin chemotherapy for a total of six courses. After chemotherapy, enhanced computed tomography showed considerable absorption of pleural effusion, and a left lobe pulmonary nodule was not detected. The postoperative pathological diagnosis was PB, and epithelial and mesenchymal differentiation components were observed. The patient continued to visit the hospital regularly for re-examination and imaging examinations. Currently, no signs of recurrence or distant metastasis have been detected.

Funder

This work was supported by the National Natural Science Foundation of China

Publisher

SAGE Publications

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