A Multicentre Trial with Bacampicillin (Penglobe®) in the Treatment of Respiratory Tract Infections in General Practice

Author:

Pauwels R1,Detiège J J2

Affiliation:

1. University of Gent, De Pintelaan 185, B-9000 Gent, Belgium

2. Chaussée d'Anvers 280, B-1000 Brussels, Belgium

Abstract

Nine hundred and eleven patients were admitted to a multicentre trial with bacampicillin (Penglobe®) in respiratory tract infections. Of these it was possible to evaluate 830 with respect to efficacy and side-effects. In most cases a dosage of 400 mg × 2 was used but in severe cases 800 mg × 2 was used. The clinical outcome was assessed as good for 79% of the patients, while 17% showed an improvement and 3% a failure. The tolerance was good with an over-all incidence of 8% side-effects, of which dyspepsia was the most common.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Reference9 articles.

1. Davies B I, Maesen F P V (1978) Ampicillin and bacampicillin in chronic bronchitis. In: Siegenthaler E, Luethy R, (Eds), Current Chemotherapy I, Proceedings of the 10th International Congress of Chemotherapy, Zürich 1977. American Society for Microbiology, Washington p 622.

2. Pharmacological and Clinical Study of Bacampicillin in Acute Peritonsillitis–a Comparison with Ampicillin

3. Review of side-effects of aminopenicillins

4. Clinical Study on Bacampicillin in Otitis Media Acuta and Sinusitis Acuta

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