Blood pressure and cognitive function among older adults in India

Author:

Farron Madeline R.1,Kabeto Mohammed U.1,Levine Deborah A.123,Wixom Caroline R.1ORCID,Langa Kenneth M.13456

Affiliation:

1. General Medicine, Department of Internal Medicine, University of Michigan, University of Michigan, Ann Arbor, MI, USA

2. Department of Neurology, University of Michigan, Ann Arbor, MI, USA

3. Institute for Healthcare Policy and Innovation, University of Michigan, University of Michigan, Ann Arbor, MI, USA

4. Institute for Social Research, University of Michigan, Ann Arbor, MI, USA

5. Institute of Gerontology, University of Michigan, Ann Arbor, MI, USA

6. Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA

Abstract

Objective We aimed to investigate the relationship between blood pressure and cognitive function among older adults in India. Methods In this study, we analyzed cross-sectional data of systolic and diastolic blood pressure (SBP and DBP, respectively) and cognitive testing from 3690 adults aged 60 years and older participating in the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia from 14 states in India. Results After controlling for key sociodemographic, health, and geographic factors, higher SBP and lower DBP were each independently associated with worse cognitive function. Older age, female sex, lower education level, being widowed, residing in a rural area, being a member of a Scheduled Caste or Scheduled Tribe, having a low level of economic consumption, being underweight, and a history of stroke were all independently associated with worse cognitive function scores. Conclusions Both SBP and DBP were independently associated with cognitive function among older adults in India in diverging directions. Clinical interventions targeting high SBP and low DBP may benefit both cognitive health and cardiovascular health.

Funder

National Institutes of Health

National Institute on Aging

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

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