Coexistence of primary thyroid diffuse large B cell lymphoma and papillary thyroid carcinoma: a case report and literature review

Abstract

Primary thyroid lymphoma (PTL) is a very rare type of thyroid malignant tumor. PTL coexisting with papillary thyroid carcinoma (PTC) is even scarcer and can be easily overlooked. We present our experience of the diagnosis and treatment of a 37-year-old woman with primary thyroid diffuse large B cell lymphoma complicated with PTC. We also considered this case in the context of previous reports. The results indicated that the incidence of concurrent Hashimoto’s disease varied among patients with different lymphoma subtypes, with the highest incidence in patients with mucosa-associated lymphoid tissue lymphoma. Furthermore, thyroid cancer and thus the combination of PTL and PTC were more common in women.