Intratympanic dexamethasone for managing pregnant women with sudden hearing loss

Author:

Fu Yaoyao1,Jing Jianghua1,Ren Tongli1,Zhao Hui1

Affiliation:

1. ENT Institute, Eye & ENT Hospital of Fudan University, Shanghai, China

Abstract

Objective This study aimed to investigate the effect and safety of intratympanic dexamethasone in pregnant women with idiopathic sudden sensorineural hearing loss (ISSNHL). Methods We performed a prospective study on pregnant women who suffered from ISSNHL and were treated in our clinic during 2016. The patients received intratympanic treatment three to four times a week. A pure tone audiogram (PTA) was performed before treatment and patients were followed up until 2 months after treatment was finished. Results A total of six pregnant women were included. All of the patients tolerated intratympanic treatment well. The mean improvement in hearing was 48 ± 7.33 dB. There were no complications, including permanent perforation of the ear drum or middle ear infection. Each patient delivered a healthy newborn. Conclusion Intratympanic dexamethasone is effective and safe for treating pregnant women with ISSNHL. Further randomized, controlled studies on this treatment need to be performed.

Funder

National Natural Fund Committee

Shanghai Science and Technology Committee

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

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1. Risk Factors, Complications, and Treatment Modalities for Sudden Sensorineural Hearing Loss in Pregnant Women: A Systematic Review and Meta-analysis;Noise and Health;2024-04

2. Pregnant Patients with Sudden Sensorineural Hearing Loss: Treatments and Efficacy;The Journal of International Advanced Otology;2023-12-01

3. Otologic and Neurotologic Disorders in Pregnancy;Neurological Disorders in Pregnancy;2023

4. ENT Emergencies During Pregnancy;ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation;2022

5. Sudden Sensorineural Hearing Loss During Pregnancy and the Postpartum Period;ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation;2022

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