Comparison between Two Non-Halogenated Glucocorticoid Ointments in Psoriasis

Author:

Heijer A1,Hesser G1,Holm P1,Salde L2

Affiliation:

1. Department of Dermatology, Regional Hospital, Uddevalla, Sweden

2. Medical Department, AB DRACO/TIKA (a subsidiary to AB ASTRA, Sweden), Lund, Sweden

Abstract

Observations made in a controlled double-blind investigation of two non-halogenated topical steroids, hydrocortisone-17-butyrate (HCB) and budesonide in thirty-six patients with psoriasis revealed a clear difference in therapeutic effect between the two ointments, indicating that they belong to different groups of topical steroids according to a classification accepted in the Nordic countries. Budesonide had a good therapeutic effect in all the patients studied, while, as a rule, HCB was clearly less effective.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

Reference11 articles.

1. Bleeker J, Edeland B, Eilard U, Gisslén H, Hersle K, Konstman-Meier C H, Kuokkanen K, Larsson R, Lassos L, Nordin P, Nörholm A, Svensson L, Thybo H, Unna P J, Wikström K (1980) Long-term multicentre clinical investigation of budesonide 0.025% ointment in psoriasis. In: ‘Abstracts’ the 22nd Nordic Conference on Dermatology, Helsinki. Editors: Mustakallio K and Förström L. p 178.

2. THE EFFECT ON ADRENAL FUNCTION OF TREATMENT OF ECZEMA AND PSORIASIS WITH TRIAMCINOLONE ACETONIDE

3. Cushing Syndrome From Percutaneous Absorption of Triamcinolone Cream

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