Effect of the Standardized Ginseng Extract G115® on the Metabolism and Electrical Activity of the Rabbit's Brain-Reference-Cited by-同舟云学术

Effect of the Standardized Ginseng Extract G115® on the Metabolism and Electrical Activity of the Rabbit's Brain

Published:1985-11 Issue:6 Volume:13 Page:342-348
ISSN:0300-0605
Container-title:Journal of International Medical Research
language:en
Short-container-title:J Int Med Res

Author:

Samira M M Hassan¹,Attia M Attia¹,Allam M¹,Elwan Osamah¹

Affiliation:

1. Departments of Pharmacology and Therapeutics, Physiology and Neurology, Cairo and Ain Shams Universities, Cairo, Egypt

Abstract

The objective of this original investigation was to study the effect of the standardized Ginseng Extract G115* on the metabolic activity and ECoG of the rabbit's brain. The results showed significant increase of the glucose uptake with simultaneous significant reduction of the lactate, pyruvate and lactate/pyruvate ratio. These findings indicate shift of glucose utilization by the drug from anaerobic to the more economical pathway. G115 was also shown to produce a desynchronizing effect on the electrocorticogram (ECoG) which correlated well with the biochemical findings.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/030006058501300608

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