The Use of Cimetropii Bromidum as Premedication for Endoscopy of the Upper Gastro-Intestinal Tract: A Double-Blind Controlled Clinical Trial

Author:

Parente F1,Lazzaroni M2,Imbimbo B P1,Panza E1,Ardizzone S1,Porro G Bianchi3

Affiliation:

1. Junior Assistant, Gastro-Intestinal Unit, L. Sacco Hospital, Milan, Italy

2. Senior Assistant, Gastro-Intestinal Unit, L. Sacco Hospital, Milan, Italy

3. Head of Unit, Gastro-Intestinal Unit, L. Sacco Hospital, Milan, Italy

Abstract

The effectiveness of cimetropii bromidum (10 or 20 mg i.v.) as premedication for upper gastro-intestinal tract endoscopy was examined and compared with that of placebo in a double-blind crossover study involving 160 patients. The drug effects were assessed from the degree of opening of the pyloric sphincter and the endoscopist's rating of drug performance. The study showed that the effects of cimetropii bromidum differed highly significantly (p < 0·0001) from those of placebo, on either count. No adverse effects were noted.

Publisher

SAGE Publications

Subject

Biochemistry (medical),Cell Biology,Biochemistry,General Medicine

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