Preparation and Properties of Modified Chitosan Films for Drug Release-Reference-Cited by-同舟云学术

Preparation and Properties of Modified Chitosan Films for Drug Release

Published:1995-10 Issue:4 Volume:10 Page:285-298
ISSN:0883-9115
Container-title:Journal of Bioactive and Compatible Polymers
language:en
Short-container-title:Journal of Bioactive and Compatible Polymers

Author:

Angelova N.¹,Manolova N.²,Rashkov I.¹,Maximova V.³,Bogdanova S.⁴,Domard A.⁵

Affiliation:

1. Institute of Polymers, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria

2. Institute of Polymers, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria,

3. Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria

4. Faculty of Pharmacy, Academy of Medicine, 1000 Sofia, Bulgaria

5. Laboratoire d'Etudes des Métariaux Plastiques et des Biomatériaux URA-CNRS 507, Université Claude Bernard Lyon I, 69622 Villeurbanne Cedax, France

Abstract

A novel method of preparing modified chitosan films was developed. Bi- and tri-component chitosan films were prepared by blending chitosan with high molecular weight polyoxyethylene. The films were loaded with 8-hydroxy-7-iodoquinoline-5-sulfonic acid which was chosen as a model drug. The properties of the films were studied with respect to crystallinity, thermal stability and swelling degree. These properties were shown to depend on the ratio of polyoxyethylene/chitosan. The drug release profile from the films was measured in a buffer at pH 6.8 and 37°C. The antimycotic effect of the films against Candida albicans was determined.

Publisher

SAGE Publications

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Link

http://journals.sagepub.com/doi/pdf/10.1177/088391159501000401

Reference23 articles.

1. Chitosan: A Biocompatible Material for Oral and Intravenous Administrations

2. Advances in Chitin and Chitosan

3. 5. Olsen, R. A., D. Schwartzmiller, W. W. Weppner and R. Winandy. 1989. Chitin and Chitosan, Proc. 4th Intern. Conf Chitin and Chitosan. G. Skjiak-Braek, T. Anthonsen and P. Sandford, eds. London: Elsevier Applied Science Publishers, p. 813.

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