Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity-Reference-Cited by-同舟云学术

Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity

Published:2021-01 Issue: Volume:19 Page:228080001882225
ISSN:2280-8000
Container-title:Journal of Applied Biomaterials & Functional Materials
language:en
Short-container-title:Journal of Applied Biomaterials & Functional Materials

Author:

Magić Marko¹,Čolović Božana²,Vasilijić Saša³,Tadić Nenad⁴,Stojadinović Stevan⁴,Jokanović Vukoman²⁵

Affiliation:

1. School of Dentistry, University of Belgrade, Belgrade, Serbia

2. Vinča Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia

3. Institute for Medical Research, Military Medical Academy, Medical Faculty MMA, University of Defence, Belgrade, Serbia

4. Faculty of Physics, University of Belgrade, Belgrade, Serbia

5. ALBOS d.o.o., Belgrade, Serbia

Abstract

The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Bioengineering,Biophysics

Link

http://journals.sagepub.com/doi/pdf/10.1177/2280800018822252

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