Affiliation:
1. Washington University in St. Louis, MO, USA
2. Brown University, Providence, RI, USA
Abstract
A clinical consequence of symptomatic Alzheimer’s disease (AD) is impaired driving performance. However, decline in driving performance may begin in the preclinical stage of AD. We used a naturalistic driving methodology to examine differences in driving behavior over one year in a small sample of cognitively normal older adults with ( n = 10) and without ( n = 10) preclinical AD. As expected with a small sample size, there were no statistically significant differences between the two groups, but older adults with preclinical AD drove less often, were less likely to drive at night, and had fewer aggressive behaviors such as hard braking, speeding, and sudden acceleration. The sample size required to power a larger study to determine differences was calculated.
Funder
Washington University in St. Louis
National Center for Advancing Translational Sciences
Neuroimaging Informatics and Analysis Center
National Institute on Aging
Subject
Geriatrics and Gerontology,Gerontology
Cited by
29 articles.
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