Review: Ulcerative colitis: current treatment strategies and future prospects-Reference-Cited by-同舟云学术

Review: Ulcerative colitis: current treatment strategies and future prospects

Published:2009-03 Issue:2 Volume:2 Page:99-108
ISSN:1756-2848
Container-title:Therapeutic Advances in Gastroenterology
language:en
Short-container-title:Therap Adv Gastroenterol

Author:

Garud Sagar¹,Peppercorn Mark A.²

Affiliation:

1. Dept of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA, sgarud@bidmc. harvard.edu

2. Dept of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

Abstract

Ulcerative colitis (UC) is a disease of unknown etiology characterized by inflammation of the mucosa and occasionally the submucosa of the colon. Conventional drug therapy for UC involves use of aminosalicylates, corticosteroids, azathioprine/6-mercaptopurine, cyclosporine and anti-tumor necrosis factor therapy. Alternative therapies include probiotics, nicotine and fish oil. Drugs like tacrolimus, rosiglitazone and Trichuris suis ova are being evaluated for use in UC patients. With the new biologic agents, new treatment options for UC continue to evolve. In this article we will discuss the conventional drugs, the alternative therapies and the management strategies according to the severity and extent of UC.

Publisher

SAGE Publications

Subject

Gastroenterology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1756283X09102329

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