Tailoring graft strategy to calcification severity of aorta in off-pump coronary artery bypass grafting

Author:

Nakamura Yoshitsugu1,Nakajima Hiroyuki1,Morita Kozo1,Okada Norihiro1,Tabata Mimiko1,Koike Hiroyuki1,Kambe Masaru1,Uwabe Kazuhiko1,Asakura Toshihisa1,Iguchi Atsushi1,Kimura Fumiko2,Niinami Hiroshi1

Affiliation:

1. The Department of Cardiovascular Surgery, Saitama International Medical Center, Saitama Medical University, Saitama, Japan

2. Department of Radiology, Saitama International Medical Center, Saitama Medical University, Saitama, Japan

Abstract

Background: The study aimed to assess the influence of the calcification of the ascending aorta on surgical mortality, postoperative stroke, and completeness of coronary revascularization in patients undergoing off-pump coronary artery bypass grafting with graft strategy tailored to its calcification severity. Methods and results: We examined the clinical records of 726 patients who underwent off-pump coronary artery bypass grafting. The age at operation was 71 ± 8 years. Calcification of the ascending aorta was graded as none–mild (less than spotty) in 668 (92.0%), moderate (<1/4 of circumference) in 26 (3.6%), and severe (>1/4) in 32 (4.4%) by preoperative non-contrast computed tomography. There were no significant differences in the number of distal anastomoses per patient among the three groups (3.3 ± 1.1, 2.9 ± 1.0, and 3.0 ± 0.9, respectively; p = 0.85). Graft strategy was tailored for each patient. Proximal anastomosis with partial clamp was used in 43.8%, 7.7%, and 3.1%, respectively (p < 0.001), while anastomotic devices were used in 6.8%, 30.1%, and 28.1%, respectively (p < 0.001). Other patients had aortic no-touch technique. There were four hospital deaths in the none–mild group (0.6%, p = 0.85). Stroke occurred in 1 (0.1%) patient, an aortic no-touch technique patient with none–mild calcification. Complete revascularization was not possible in 1 (0.1%) patient in the severe calcification group. Patency of saphenous vein graft of distal anastomosis was not different among groups. Conclusion: Influence of the calcification of the ascending aorta was minimized by tailoring graft strategy to calcification severity. It can practically abolish postoperative stroke while maintaining coronary revascularization success rates.

Publisher

SAGE Publications

Subject

Pharmacology

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