Psychosocial factors associated with health-related quality of life in patients with chronic disease: Results of a cross-sectional survey

Author:

Van Wilder Lisa1ORCID,Vandepitte Sophie1,Clays Els1,Devleesschauwer Brecht23ORCID,Pype Peter1,Boeckxstaens Pauline1,Schrans Diego1,De Smedt Delphine1

Affiliation:

1. Department of Public Health and Primary Care, Ghent University, Ghent, Belgium

2. Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium

3. Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium

Abstract

Objective The impact of various psychosocial factors (sense of coherence, illness perception, patient enablement, self-efficacy, health literacy, personality) is not fully understood across a wide range of chronic diseases, and in particular in patients with multimorbidity. As such, this study assessed the key psychosocial factors associated with impaired health-related quality of life (HRQoL) in patients with one or more chronic diseases based on cross-sectional data collected in Flanders (Belgium). Methods Cross-sectional data on 544 chronically ill patients were analysed. Multiple linear regression models were built to analyze the key psychosocial factors associated with HRQoL (EQ-5D-5Lindex as dependent factor). Results Overall, the strongest independently associated factor with HRQoL was illness perceptions (β = −0.52, P < 0.001). In addition, sense of coherence (β = 0.14, P = < 0.05) was independently positively associated with HRQoL. Moreover, after stratification for multimorbidity, the negative association of illness perceptions with HRQoL was stronger when multimorbidity is present compared to when it is absent (β = −0.62, P < 0.001 vs β = −0.38, P < 0.001). Conclusions This study revealed interesting associations of the modifiable psychosocial factors of illness perceptions and sense of coherence with HRQoL in a population of chronically ill persons. Given that the burden of chronic diseases will rise in the next decades, designing and implementing interventions that enhance these psychosocial abilities of patients, especially illness perceptions in multimorbid patients, is needed in order to reduce the burden of chronic diseases in terms of impaired HRQoL.

Funder

Bijzonder Onderzoeksfonds

Publisher

SAGE Publications

Subject

Health Policy,General Medicine

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