Usefulness of polymerase chain reaction analysis in a case of clinically and histologically atypical nodular granulomatous secondary syphilis-Reference-Cited by-同舟云学术

Usefulness of polymerase chain reaction analysis in a case of clinically and histologically atypical nodular granulomatous secondary syphilis

Published:2023-08-25 Issue:11 Volume:34 Page:823-825
ISSN:0956-4624
Container-title:International Journal of STD & AIDS
language:en
Short-container-title:Int J STD AIDS

Author:

Falcinelli Francesca¹^ORCID,Trovato Emanuele¹,Baldino Gennaro²,Miracco Clelia³,Rubegni Pietro¹,De Piano Ernesto¹

Affiliation:

1. Dermatology Unit, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy

2. Section Legal Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy

3. Section of Pathology, Department of Medical Biotechnology, University of Siena, Siena, Italy

Abstract

We report a case of a nodular granulomatous secondary syphilis histologically resembling tuberculids in a patient with positive quantiferon test and serology for syphilis. Polymerase chain reaction (PCR) analysis led to the diagnosis. We underline the usefulness of PCR in clinically and histologically doubtful cases in order to avoid misdiagnosis and delay treatment.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/09564624231193497

Reference7 articles.

1. Syphilis

2. The great imitator revisited: the spectrum of atypical cutaneous manifestations of secondary syphilis

3. Granulomatous secondary syphilis: Another diagnostic pitfall for the dermatopathologist

4. Nodular secondary syphilis with associated granulomatous inflammation: case report and literature review

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