HIV infections among female sex workers in Mombasa, Kenya: current prevalence and trends over 25 years

Author:

Manguro Griffins O1ORCID,Gichuki Carol1,Ampt Frances H23,Agius Paul A23,Lim Megan SC23,Jaoko Walter G4,Hellard Margaret2356,L’Engle Kelly7,Stoové Mark23,Mandaliya Kishor8,Chersich Matthew F9,Temmerman Marleen11011,Luchters Stanley231213,Gichangi Peter11114

Affiliation:

1. International Centre for Reproductive Health Kenya, Mombasa, Kenya

2. Burnet Institute, Melbourne, Australia

3. School of Population Health and Preventive Medicine, Monash University, Melbourne, Australia

4. Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya

5. Doherty Institute, University of Melbourne, Melbourne, Australia

6. Department of Infectious Diseases, Alfred Hospital Melbourne, Melbourne, Australia

7. Department of Population Health Sciences, University of San Francisco, San Francisco, CA, USA

8. Pathcare Laboratories, Mombasa, Kenya

9. Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

10. Department of Obstetrics and Gynaecology, Aga Khan University Hospital, Nairobi, Kenya

11. Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium

12. International Centre for Reproductive Health, Department of Obstetrics and Gynaecology, Ghent University, Ghent, Belgium

13. Department of Population Health, Aga Khan University, Nairobi, Kenya

14. Technical University of Mombasa, Mombasa, Kenya

Abstract

Over 20 years, interventions have targeted HIV among female sex workers (FSWs) in Kenya given their central role in new infections. To determine the effects of these interventions, we assessed the prevalence and correlates of HIV among a random sample of FSWs and modelled prevalence estimates from studies since 1993. FSWs aged 16–34 years were enrolled through multi-stage sampling. Regression models identified correlates of HIV infection. Generalised linear mixed modelling estimated temporal changes in prevalence between 1993 and 2016. 882 FSWs were enrolled. Prevalence rose from 3.6% among 16–20-year-olds to 31.6% among 31–34-year-old FSWs. Those aged 31 to 34 years had greater odds of HIV compared to those 16 to 20 years (AOR 14.2, 95% CI, 5.5–36.8). Infection was less prevalent among FSWs with tertiary education compared to those with primary or no education (AOR 0.23, 95% CI, 0.07–0.78). There was an overall 30% reduction in prevalence from 1993 to 2016 with an average annual decline of 3%. About one in ten FSWs in Mombasa are currently infected with HIV. Considering FSWs’ central role in sustaining population-level infections, these initiatives require continued support, focusing on reducing transmission from older FSWs and those with less education.

Funder

Australia’s National Health and Medical Research Council

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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