Successful treatment of high-grade vulval intra-epithelial neoplasia with imiquimod 5% in a renal transplant recipient-Reference-Cited by-同舟云学术

Successful treatment of high-grade vulval intra-epithelial neoplasia with imiquimod 5% in a renal transplant recipient

Published:2018-10-04 Issue:2 Volume:30 Page:198-200
ISSN:0956-4624
Container-title:International Journal of STD & AIDS
language:en
Short-container-title:Int J STD AIDS

Author:

Khatun Azra¹,Lotery Helen²,Sundaram Sangeetha³^ORCID

Affiliation:

1. School of Medicine, University of Southampton, Southampton, UK

2. Department of Dermatology, University Hospital Southampton NHS Foundation Trust, Southampton, UK

3. Department of GU Medicine, Solent NHS Trust, Southampton, UK

Abstract

Organ transplant recipients are at a higher risk of pre-malignant human papillomavirus-associated lesions due to immunosuppression. The efficacy of immunomodulants such as imiquimod 5% is not yet fully evaluated in this population. We describe a case of vulval intra-epithelial neoplasia in a renal transplant recipient which was successfully treated with topical imiquimod.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0956462418797244

Reference19 articles.

1. In situ and invasive squamous cell carcinoma of the vulva in Denmark 1978–2007—a nationwide population-based study

2. The 2015 International Society for the Study of Vulvovaginal Disease (ISSVD) Terminology of Vulvar Squamous Intraepithelial Lesions

3. Prevalence and type distribution of human papillomavirus in squamous cell carcinoma and intraepithelial neoplasia of the vulva

4. Immunomodulatory and pharmacologic properties of imiquimod