HIV care cascade for women living with HIV in the Greater Toronto Area versus the rest of Ontario and Canada

Author:

Medeiros Priscilla1ORCID,Warren Laura12,Kazemi Mina1,Massaquoi Notisha3,Smith Stephanie1,Tharao Wangari4,Serghides Lena156,Logie Carmen H13ORCID,Kroch Abigail7,Burchell Ann N89,de Pokomandy Alexandra1011ORCID,Kaida Angela12,Loutfy Mona129ORCID,

Affiliation:

1. Women’s College Research Institute, Women’s College Hospital, Toronto, ON, Canada

2. Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

3. Faculty of Social Work, University of Toronto, Toronto, ON, Canada

4. Women’s Health in Women’s Hands Community Health, Toronto, ON, Canada

5. Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada

6. Department of Immunology, University of Toronto, Toronto, ON, Canada

7. Ontario HIV Treatment Network, Toronto, ON, Canada

8. Department of Family and Community Medicine, St. Michael’s Hospital, Toronto, ON, Canada

9. Faculty of Medicine, University of Toronto, Toronto, ON, Canada

10. Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada

11. Department of Family Medicine, McGill University, Montreal, QC, Canada

12. Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada

Abstract

Background The Greater Toronto Area (GTA) is home to 39% of Canada’s population living with HIV. To identify gaps in access and engagement in care and treatment, we assessed the care cascade of women living with HIV (WLWH) in the GTA versus the rest of Ontario and Canada (in this case: Quebec and British Columbia). Methods We analyzed 2013–2015 self-reported baseline data from the Canadian HIV Women’s Sexual and Reproductive Health Cohort Study for six care cascade stages: linked to care, retained in care, initiated antiretroviral therapy (ART), currently on ART, ART adherence (≥90%), and undetectable (<50 copies/mL). Multivariable logistic regression was used to reveal associations with being undetectable. Results Comparing the GTA to the rest of Ontario and Canada, respectively: 96%, 98%, 100% were linked to care; 92%, 94%, 98% retained in care; 72%, 89%, 96% initiated ART; 67%, 81%, 90% were currently using ART; 53%, 66%, 77% were adherent; 59%, 69%, 81% were undetectable. Factors associated with viral suppression in the multivariable model included: living outside of the GTA (Ontario: aOR = 1.72, 95% CI: 1.09–2.72; Canada: aOR = 2.42, 95% CI: 1.62–3.62), non-Canadian citizenship (landed immigrant/permanent resident: aOR = 3.23, 95% CI: 1.66–6.26; refugee/protected person/other status: aOR = 4.77, 95% CI: 1.96–11.64), completed high school (aOR = 1.77, 95% CI: 1.15–2.73), stable housing (aOR = 2.13, 95% CI: 1.33–3.39), income of ≥$20,000 (aOR = 1.52, 95% CI: 1.00–2.31), HIV diagnosis <6 years (6–14 years: aOR = 1.75, 95% CI: 1.16–2.63; >14 years: aOR = 1.87, 95% CI: 1.19–2.96), and higher resilience (aOR = 1.02, 95% CI: 1.00–1.04). Conclusion WLWH living in the GTA had lower rates of viral suppression compared to the rest of Ontario and Canada even after adjustment of age, ethnicity, and HIV diagnosis duration. High-impact programming for WLWH in the GTA to improve HIV outcomes are greatly needed.

Funder

Canadian Institutes of Health Research

Canadian HIV Trials Network, Canadian Institutes of Health Research

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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