Successful treatment of trichomoniasis with tinidazole following desensitization in a patient allergic to metronidazole

Author:

Biagi Mark12ORCID,Slipke Wendy2,Smalley Alexa2,Tsaras Geoffrey3

Affiliation:

1. College of Pharmacy, University of Illinois at Chicago, Rockford, IL, USA

2. Department of Pharmacy, SwedishAmerican Hospital, Rockford, IL, USA

3. Division of Infectious Diseases, Department of Medicine, SwedishAmerican Hospital, Rockford, IL, USA

Abstract

Metronidazole desensitization is recommended in patients with trichomoniasis and history of an allergic reaction to metronidazole due to presumed cross reactivity with tinidazole and lack of reliably safe and effective alternative therapies. We report our experiences in a patient with persistent trichomoniasis who failed to complete metronidazole desensitization due to a burning sensation over her whole body and pruritus but was later successfully desensitized to tinidazole without experiencing any adverse effects.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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