Beyond HIV prevention: Assessment of the benefits of pre-exposure prophylaxis for sexual quality of life

Author:

Bertevello Daniel A1ORCID,Vasconcelos Ricardo1,Cerqueira Natalia B1,Freitas Angela C1,Cunha Ana1,Avelino-Silva Vivian I1ORCID

Affiliation:

1. Department of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

Abstract

Background Pre-exposure prophylaxis (PrEP) may favor sexual satisfaction by reducing the fear of HIV and promoting less restrictive sexual practices. These benefits may be even higher among PrEP users with mental health issues. Methods We invited adult PrEP users to answer a questionnaire including demographics, questions on the sexual experience compared to the period before PrEP use, and the Hospital Anxiety and Depression Scale. Factors associated with improvements in the sexual experience were investigated using modified Poisson models. Results We included 221 participants; most were white males. A large percentage of participants reported improvements in quality of sex after PrEP initiation; the composite outcome “PrEP-associated improvement in the quality of sex” was observed in 92 (42%), whereas the outcome “PrEP-associated improvement in the fear of HIV acquisition” was observed in 120 participants (54%). Demographics and depression/anxiety were not significantly associated with the outcomes. Conclusion PrEP has positive effects beyond HIV prevention, improving several aspects of sexual quality of life. These benefits are valid incentives for PrEP use and prescription.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

Reference23 articles.

1. In Danger: UNAIDS Global AIDS Update 2022

2. Segal K. The evolution of oral PrEP access: tracking trends inglobal oral PrEP use over time. 2021 (accessed on 28 January 2021).

3. What will it take to meet UNAIDS targets for preexposure prophylaxis users?

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