Are You Sure It's Syphilis? A Review of False Positive Serology

Author:

Nandwani R1,Evans D T P2

Affiliation:

1. Department of GU/HIV Medicine, King's Healthcare, 15-22 Caldecot Road, London SE5 9RS, UK

2. Sexual Health Service, Fremantle Hospital, Alma Street, Fremantle WA 6160, Australia

Abstract

Summary: This article on false positive serological reactions for syphilis reviews the rapid developments which have taken place in the serodiagnosis of syphilis in recent years since the advent of the AIDS epidemic. An overview of non-specific and specific treponemal serological tests in relation to acute and chronic biological false positive reactions is followed by closer consideration of syphilis serology in the context of HIV infection, pregnancy and other conditions which may produce false positive reactions.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

Reference63 articles.

1. Robertson DHH, McMillan A, Young H. Diagnosis of syphilis. In: Clinical practice in sexually transmissible diseases. Edinburgh: Churchill Livingstone, 1989;131–2.

2. Biological True and False Serological Tests for Syphilis: Their Relationship with Anticardiolipin Antibodies

3. Treatment of Early Latent Syphilis of Less than a Yearʼs Duration

4. Treatment of Primary and Secondary Syphilis

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