Soluble Interleukin-2 Receptors in Serum and Urine of Patients with Chancroid and Their Response to Therapy

Author:

Abeck D1,Korting H C1,Zaba R1,Dangor Y2,Fehler G2,Ballard R C2

Affiliation:

1. Department of Dermatology, Ludwig-Maximilians-University, Munich, FRG

2. Emergent Pathogen Research Unit of the South African Medical Research Council, School of Pathology, University of Witwatersrand and South African Institute for Medical Research, Johannesburg, South Africa

Abstract

To investigate cell-mediated immune response in chancroid, soluble interleukin-2 receptor levels in serum and urine samples of healthy individuals and patients were measured by an enzyme-linked immunosorbent assay. Increased levels both in serum and in urine were observed in cases of Haemophilus ducreyi infection. In patients showing a prolonged incubation period, urine levels exceeded serum values. Therapy led to a reduction of elevated interleukin-2 receptor levels in serum and in urine.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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