A Case of Coccidioidal Meningitis With Biofilm Obstructing VP Shunt Due to Cutibacterium acnes

Author:

Sharma Rupam12ORCID,Johnson Royce H.12,David Gerard R.3,Rahimifar Majid4,Heidari Arash12ORCID

Affiliation:

1. Kern Medical, Bakersfield, CA, USA

2. University of California, Los Angeles, USA

3. Kaiser Permanente, Bakersfield, CA, USA

4. Bakersfield Memorial Hospital, CA, USA

Abstract

Herein described is a case of biofilm obstructing ventriculoperitoneal shunt due to Cutibacteirum acnes infection in a patient with coccidioidal meningitis. Cutibacterium acnes infects and obstructs cerebral shunts by the production of biofilm; however, diagnosis is usually missed by routine aerobic cultures. Obtaining anaerobic cultures routinely in patients with foreign body implants leading to central nervous system infections could prevent a missed diagnosis of this pathogen. Penicillin G is the first-line treatment.

Publisher

SAGE Publications

Subject

Safety Research,Safety, Risk, Reliability and Quality,Epidemiology

Reference14 articles.

1. Cutibacterium (formerly Propionibacterium) acnes infections associated with implantable devices

2. 2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis

3. Ventricular shunt infections: Immunopathogenesis and clinical management

4. Wang KW, Chang WN, Shih TY, et al. Infection of cerebrospinal fluid shunts: causative pathogens, clinical features, and outcomes. Jpn J Infect Dis. 2004;57(2):44-48. Accessed February 24, 2023. http://www.ncbi.nlm.nih.gov/pubmed/15118207

5. Bacteria causing ventriculoperitoneal shunt infections in a Kenyan population

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