A Case of Concurrent Disseminated Coccidioidomycosis and Embryonal Carcinoma When Lice and Fleas Coexist

Author:

Ke Michael12,Heidari Arash12ORCID,Valdez Michael3ORCID,Tsiyer Allen3,Kuran Rasha12,Johnson Royce12

Affiliation:

1. Department of Internal Medicine, Division of Infectious Diseases, UCLA at Kern Medical Center, Bakersfield, CA, USA

2. Valley Fever Institute, Bakersfield, CA, USA

3. Department of Internal Medicine, UCLA at Kern Medical Center, Bakersfield, CA, USA

Abstract

Coccidioidomycosis (CM) is a fungal infection endemic to the southwestern United States with a wide range of clinical presentations depending on the infected organ systems. Most infections are asymptomatic. Coccidioidomycosis causes a primary pulmonary infection and when symptoms occur, they most often resemble community-acquired pneumonia. One percent of cases disseminate, typically via hematogenous or lymphatic spread. It is in these cases that more severe symptoms may present and potentially overlap with those characteristics of other systemic illnesses. This is a case of CM disseminated to lymph nodes in a 24-year-old man with concomitant metastatic embryonal carcinoma. It is difficult to identify the primary etiology for many components of this patient’s presentation, including diffuse lymphadenopathy and multiple pulmonary nodules. Furthermore, the relationship between these 2 concurrent disease processes is not entirely clear. Factors that may contribute include the well-known phenomenon of locus minoris resistentiae (LMR) or potentially a shared immune failure between infectious organisms and malignant cells.

Publisher

SAGE Publications

Subject

Safety Research,Safety, Risk, Reliability and Quality,Epidemiology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. What You See Is Not What You Get: Germ Cell Tumor Mimicking Disseminated Coccidioidomycosis;Journal of Investigative Medicine High Impact Case Reports;2023-01

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