Hepatitis C Treatment Outcomes in Persons With HIV and Decompensated Cirrhosis Using a Collaborative Multidisciplinary HIV-Centered Approach-Reference-Cited by-同舟云学术

Hepatitis C Treatment Outcomes in Persons With HIV and Decompensated Cirrhosis Using a Collaborative Multidisciplinary HIV-Centered Approach

Published:2021-01-01 Issue: Volume:20 Page:232595822110247
ISSN:2325-9582
Container-title:Journal of the International Association of Providers of AIDS Care (JIAPAC)
language:en
Short-container-title:J Int Assoc Provid AIDS Care

Author:

Cachay Edward R.¹^ORCID,Mena Alvaro²,Morano Luis³^ORCID,Benitez Laura⁴,Maida Ivana⁵^ORCID,Mendoza Carmen DE⁴,Hill Lucas⁶,Torriani Francesca¹,Soriano Vincente⁷,Mathews W. C.¹,

Affiliation:

1. Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, CA, USA

2. U Enfermedades Infecciosas, S Medicina Interna, University Hospital of La Coruña, Spain

3. Unit of Infectious Diseases, University Hospital Álvaro Cunqueiro; Vigo, Spain

4. Puerta de Hierro Research Institute and University Hospital, Madrid, Spain

5. Department of Medical, Surgical, and Experimental Sciences, University of Sassari, Sassari, Italy

6. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, CA, USA

7. UNIR Health Sciences School & Medical Center, Madrid, Spain

Abstract

Fifty-four consecutive persons with HIV co-infected with hepatitis C virus (HCV) and liver decompensation were treated with direct-acting antivirals (DAA). The HCV treatment was delivered using a multidisciplinary HIV-coinfection model of care integrating sub-specialty services in 3 countries. Of those treated, 91% (95% confidence interval, 80.1 to 95.9) achieved sustained viral response, and only one person died during treatment. Our study provides evidence that HIV providers achieve excellent outcomes when treating patients with histories of decompensated liver disease, with characteristics similar to those studied using a multidisciplinary HIV-centered approach.

Funder

Pacific AIDS Education and Training Center

Publisher

SAGE Publications

Subject

Infectious Diseases,Dermatology,Immunology

Link

http://journals.sagepub.com/doi/pdf/10.1177/23259582211024771

Reference11 articles.

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