Outcomes of HIV Positive Children and Adolescents Initiated on Antiretroviral Treatment in Nigeria (2007-2016)-Reference-Cited by-同舟云学术

Outcomes of HIV Positive Children and Adolescents Initiated on Antiretroviral Treatment in Nigeria (2007-2016)

Published:2022-01 Issue: Volume:21 Page:232595822211170
ISSN:2325-9582
Container-title:Journal of the International Association of Providers of AIDS Care (JIAPAC)
language:en
Short-container-title:J Int Assoc Provid AIDS Care

Author:

Anukam Onyekachi¹,Blanco Natalia²^ORCID,Jumare Jibreel²,Lo Julia²,Babatunde Ezra¹,Odafe Solomon³,Onotu Dennis³,Ene Uzoma³,Fagbamigbe Johnson³,Carpenter Deborah⁴,Rivadeneira Emilia D.⁴,Omoigberale Austin I.⁵⁶,Charurat Manhattan²,Swaminathan Mahesh³,Stafford Kristen A.²^ORCID

Affiliation:

1. University of Maryland, Baltimore; Abuja, Nigeria

2. University of Maryland, Baltimore, MD, USA

3. Division of Global HIV & Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria

4. Division of Global HIV & Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA

5. Paediatric Association of Nigeria, Abuja, Nigeria

6. Department of Child Health, University of Benin Teaching Hospital, Benin City, Nigeria

Abstract

Background: This manuscript aimed to examine treatment outcomes of HIV-positive children and adolescents. Methods: We retrospectively analyzed data of a sample of patients aged 0–19 years who initiated ART (October 2007–September 2016) in participating sites in 30 states and the Federal Capital Territory in Nigeria. Results: Among 4006 patients alive at the end of the follow up period, 138 (3.4%) were LTFU. Adolescents had a significantly higher risk of being LTFU than children aged 3–5 years (HR 2.47 [95% CI 1.40-4.34]). Patients with advanced disease had a significantly higher risk of being LTFU (Stage IV HR, 3.66 [95% CI: 2.00-6.68]). On average, optimal ART refill adherence was met by 67.3% of patients. Conclusion: Our findings suggest that focusing on preventing and managing advanced disease and interventions supporting adolescents when transferring to adult care is warranted.

Funder

Center for Global Health

Publisher

SAGE Publications

Subject

Infectious Diseases,Dermatology,Immunology

Link

http://journals.sagepub.com/doi/pdf/10.1177/23259582221117009

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