Transfusion-Transmissible Infections Among Blood Donors in a Regional Hospital in Ghana: A 6-Year Trend Analysis (2017-2022)-Reference-Cited by-同舟云学术

Transfusion-Transmissible Infections Among Blood Donors in a Regional Hospital in Ghana: A 6-Year Trend Analysis (2017-2022)

Published:2024-01 Issue: Volume:23 Page:
ISSN:2325-9582
Container-title:Journal of the International Association of Providers of AIDS Care (JIAPAC)
language:en
Short-container-title:J Int Assoc Provid AIDS Care

Author:

Hadfield Priscilla Yeboah¹,Vechey Godwin Adjei²,Bansah Emmanuel³,Nyahe Morkporkpor²,Khuzwayo Nelisiwe⁴,Tarkang Elvis Enowbeyang¹⁴⁵^ORCID

Affiliation:

1. Department of Population and Behavioural Sciences, School of Public Health, University of Health and Allied Sciences, Ho, Ghana

2. School of Public Health, University of Health and Allied Sciences, Hohoe, Ghana

3. Volta Regional Hospital Hohoe, Hohoe, Ghana

4. Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa

5. HIV/AIDS Prevention Research Network Cameroon, Kumba, Cameroon

Abstract

Background This study determined the trends of transfusion-transmissible infections (TTIs) among blood donors in a regional hospital in Ghana from 2017 to 2022. Methods A retrospective analysis was conducted on 6339 blood donor records. Data were analyzed using STATA version 17.0 at the 0.05 significance level. Results The prevalence of TTIs was 31.4% in 2017, 13.8% in 2018, 20.4% in 2019, 9.5% in 2020, 9.6% in 2021, and 11.7% in 2022. There were significant associations between hepatitis C virus (HCV), Syphilis, and sex (OR = 2.06; 95% CI [1.29-3.30]; P = .003) and (OR = 2.28; 95% CI [1.48-3.54]; P < .001), respectively. Blood donors aged 20-29 were more likely to be infected with hepatitis B virus (OR = 1.96; 95% CI [1.28-2.99]; P = .002). Blood donors aged 40-49 had higher odds of infection with HCV (OR = 3.36; 95% CI [2.02-5.57]; P < .001) and Syphilis (OR = 3.79; 95% CI [2.45-5.87]; P < .001). Conclusion The study highlights the need to implement targeted prevention strategies for donors with a higher TTI prevalence.

Publisher

SAGE Publications

Link

https://journals.sagepub.com/doi/pdf/10.1177/23259582241274305

Reference38 articles.

1. Transfusion-Transmitted Infections and associated risk factors at the Northern Zone Blood Transfusion Center in Tanzania: A study of blood donors between 2017 and 2019

2. WHO. Blood Safety | WHO | Regional Office for Africa [Internet]. 2022. https://www.afro.who.int/health-topics/blood-safety