The Role of Antibiotic Stewardship in Promoting Appropriate Antibiotic Use

Author:

Ha David R.123,Haste Nina M.123,Gluckstein Daniel P.123

Affiliation:

1. Keck Graduate Institute School of Pharmacy, Pomona Valley Hospital Medical Center, Claremont, California (DRH)

2. University of California San Diego Health and University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, La Jolla, California (NMH)

3. Infectious Diseases, Pomona Valley Hospital Medical Center, Pomona, California (DPG)

Abstract

Antibiotics are one of the most significant medical discoveries in human history. The widespread use of antibiotics has resulted in the emergence of antibiotic-resistant pathogens. This fact, coupled with the paucity of new antibiotic developments, has spurred efforts to combat antibiotic resistance. One of the most critical components of these efforts is antibiotic stewardship, a multidisciplinary endeavor, employing a collection of interventions in a variety of health care settings with the aim of promoting appropriate utilization of antibiotics. This article describes antibiotic stewardship programs and key practices used to minimize the development and spread of antibiotic-resistant pathogens including the optimization of antibiotic pharmacokinetics and pharmacodynamics, the application of rapid diagnostic tools, and the use of computerized provider order entry tools.

Publisher

SAGE Publications

Subject

Public Health, Environmental and Occupational Health,Health Policy,Medicine (miscellaneous)

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