Pulmonary Histopathology after Cardiopulmonary Bypass with Pall LG6 Leukocyte-Depleting Filter

Abstract

There is increasing interest in the use of leukocyte-depleting filters to reduce the harmful effects of neutrophils during cardiopulmonary bypass. Pulmonary histopathology was studied in 7 patients before and after cardiopulmonary bypass. The arterial line leukocyte-depleting filter (Pall LG6) was used in 5 cases and the conventional arterial line filter (Pall Autovent) was used in 2 patients. The results showed no significant influence of the leukodepletion filter on pulmonary histopathologic changes associated with cardiopulmonary bypass.