Hypertrophic obstructive cardiomyopathy: review of surgical treatment

Author:

Price Jonathan1,Clarke Nicholas1,Turer Aslan2,Quintana Eduard3,Mestres Carlos4ORCID,Huffman Lynn1,Peltz Matthias1,Wait Michael1,Ring W Steves1,Jessen Michael1,Bajona Pietro15

Affiliation:

1. Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA

2. Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

3. Hospital Clínic de Barcelona, Cardiovascular Surgery Department, Cardiovascular Institute, University of Barcelona Medical School, Barcelona, Spain

4. Department of Cardiovascular Surgery, University Hospital of Zurich, University of Zurich, Zurich, Switzerland

5. Institute of Life Sciences, Sant’Anna School of Advanced Studies, Pisa, Italy

Abstract

Hypertrophic cardiomyopathy ranks among the most common congenital cardiac diseases, affecting up to 1 in 200 of the general population. When it causes left ventricular outflow tract obstruction, treatment is guided to reduce symptoms and the risk of sudden cardiac death. Pharmacologic therapy is the first-line treatment, but when it fails, surgical myectomy or percutaneous ablation of the hypertrophic myocardium are the standard therapies to eliminate subaortic obstruction. Both surgical myectomy and percutaneous ablation are proven safe and effective treatments; however, myectomy is the gold standard with a significantly lower complication rate and more complete and lasting reduction of left ventricular outflow tract obstruction.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

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