Clinical examination and patients’ history are not suitable for neonatal hip screening

Author:

Ziegler Christian Maximilian1,Ertl Katharina Maria1,Delius Maria2,Foerster Kai Martin3,Crispin Alexander4,Wagner Ferdinand156ORCID,Heimkes Bernhard7

Affiliation:

1. Musculoskeletal University Center Munich, Department of Orthopedics and Trauma Surgery, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany

2. Department of Obstetrics and Gynecology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany

3. Department of Neonatology, Dr. von Hauner Children’s Hospital, Ludwig-Maximilians-University Munich, Munich, Germany

4. Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-University Munich, Munich, Germany

5. Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD, Australia

6. Department of Pediatric Surgery, Dr. von Hauner Children’s Hospital, Ludwig-Maximilians-University Munich, Munich, Germany

7. Department of Pediatric Surgery, Pediatric Orthopedic Section, Klinikum Dritter Orden, Munich, Germany

Abstract

Purpose: To assess the percentage of missed developmental dysplasia of the hip, which escape the German criteria for newborn hip high-risk screening, we analyzed our data gained from the general neonatal sonographic hip screening performed at our department. The aim of the study was to determine the number of potentially belatedly treated developmental dysplasia of the hip. Methods: The data from 1145 standardized newborn hip ultrasound examinations according to the Graf technique were analyzed retrospectively comparing findings for general neonatal sonographic hip screening and high-risk screening subgroups. Results: We diagnosed developmental dysplasia of the hip in 18 of the 1145 newborns via ultrasound. A total of 10 out of 18 developmental dysplasia of the hip would have been missed by high-risk screening, which corresponds to a proportion of 55.6% false-negative results. The sensitivity of high-risk screening was only 44.4% and specificity, 78.3%. The positive predictive value was 3.2%. Family history as a screening criterion yielded false-negative results in 77.8% and false-positive results in 16.8%. In all, 83.3% of the children who were born with developmental dysplasia of the hip but not from breech position as a risk factor were false negative. The clinical examination was false negative in 88.9% and false positive in 0.6%. Conclusion: High-risk screening detected less than every second developmental dysplasia of the hip, rendering the first month as the most effective treatment window unavailable for inapparent dysplastic hips, potentially resulting in the need for more invasive treatment. Due to the high sensitivity of ultrasound in the detection of developmental dysplasia of the hip, we recommend to replace the current German high-risk screening guidelines with a general newborn screening for all neonates using Graf ultrasound in the first week of life. Level of evidence: Level II.

Publisher

SAGE Publications

Subject

Orthopedics and Sports Medicine,Pediatrics, Perinatology and Child Health

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