Effect of coronaviruses on blood vessel permeability: potential therapeutic targets-Reference-Cited by-同舟云学术

Effect of coronaviruses on blood vessel permeability: potential therapeutic targets

Published:2023-01 Issue: Volume:17 Page:175346662311622
ISSN:1753-4666
Container-title:Therapeutic Advances in Respiratory Disease
language:en
Short-container-title:Ther Adv Respir Dis

Author:

Machado Nicolle R.¹,Dias Karina T.¹,Cortes Bryan F.S.¹,Rodrigues Stephen F.²^ORCID

Affiliation:

1. Laboratory of Vascular Nanopharmacology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil

2. Laboratory of Vascular Nanopharmacology, Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1524, ICB I, sala 319, 3° andar, Butantan, Sao Paulo 05508-900, Brazil

Abstract

Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

SAGE Publications

Subject

Pharmacology (medical),Pulmonary and Respiratory Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/17534666231162252

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