Pulmonary Granulomas Associated with PAS-Positive Bodies in Brachycephalic Dogs-Reference-Cited by-同舟云学术

Pulmonary Granulomas Associated with PAS-Positive Bodies in Brachycephalic Dogs

Published:1972-09 Issue:5 Volume:9 Page:294-300
ISSN:0300-9858
Container-title:Veterinary Pathology
language:en
Short-container-title:Vet Pathol

Author:

Billups L. H.¹,Liu S. K.¹,Kelly D. F.¹,Garner F. M.¹

Affiliation:

1. Veterinary Pathology Division, Armed Forces Institute of Pathology, Washington, D.C.; The Animal Medical Center, New York, N. Y.; and the School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pa.

Abstract

Pulmonary granulomas were incidental findings at necropsy in 18 dogs, mainly of the brachycephalic breeds. These lesions were multifocal along smaller bronchi and the subpleural tissue at the margins of lobes. The granulomatous reaction contained numerous periodic acid-Schiff (PAS)-positive bodies that histochemically had reactions suggestive of a calcium-lipid-mucopolysaccharide complex. Although the cause is not clear, the location and distribution are suggestive of an inhalation or aspiration pneumonia. The shortened muzzle of brachycephalic breeds, particularly when there is concurrent upper respiratory disease, may predispose them to these bodies.

Publisher

SAGE Publications

Subject

General Veterinary

Link

http://journals.sagepub.com/doi/pdf/10.1177/030098587200900501

Reference5 articles.

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2. Luna L. G. (ed.): Manual of histologic staining methods of the Armed Forces Institute of Pathology; 3rd ed., p. 167 (Blakiston, McGraw-Hill, New York 1968)

3. Pulmonary alveolar microlithiasis

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