Bovine Aspergillosis Produced by the Inoculation of Conidiospores of Aspergillus fumigatus into a Mesenteric or Jugular Vein

Abstract

Conidiospores of Aspergillus fumigatus were inoculated during the second trimester of pregnancy into a mesenteric vein of 14 heifers and into a jugular vein of three additional heifers. Heifers were killed at intervals after inoculation. Lesions were confined largely to the placentas, livers, and lungs. Placental infection was present in seven of 14 heifers inoculated via a mesenteric vein and in the three heifers inoculated via a jugularvein. Fetal mycotic infection or lesions were not established. Two heifers inoculated via a mesenteric vein aborted. Mycotic granulomas developed in the livers and lungs.