Affiliation:
1. Pathology Division, US Army Medical Research Institute of Infectious Diseases, Frederick, Md.
Abstract
Rhesus monkeys were inoculated intravenously or intraperitoneally with various numbers of Rickettsia rickettsii. Monkeys that were given more than 104 organisms intravenously died on days 3–6 after inoculation, whereas those given less than 103 intravenously or more than 104 intraperitoneally died on day 7 or later. There was no significant difference in incidence of lesions between the early- and late-death groups. Vasculitis and thrombosis occurred most frequently in the nares, pinna of the ear, scrotal skin, and testicle. Adrenal cortical necrosis was caused by capillary thrombosis. Rickettsiae, estimated by plaque formation in culture, were most numerous in the lung and spleen.
Reference14 articles.
1. Armed Forces Institute of Pathology:
Manual of histologic staining methods;
3rd ed.
pp. 33,
85,
237
(McGraw-Hill,
New York 1968)
2. Staining Rickettsiae in Yolk-Sac Cultures
Cited by
13 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献